The Targeted Lipid Nanoparticle (tLNP) Chemistry, Manufacturing and Controls (CMC) Team (TCT) is part of Biologics CMC Development Sciences within Research & Development. The team supports the development of next-generation mRNA and targeted lipid nanoparticle therapeutics through process development, formulation development, analytical characterization, and manufacturing support.
The Lab Manager will serve as the operational lead for the tLNP laboratories, ensuring a safe, efficient, and well-organized lab environment that enables scientific productivity and program execution. This role will partner closely with scientists, engineers, facilities and EHS to support lab operations, equipment management, inventory control, safety, and site coordination activities.
Key Responsibilities
- Lead daily lab operations, maintaining scientific readiness, safety, and organization; drive continuous improvement through 5S, visual management, and operational best practices.
- Serve as the primary contact for facility, infrastructure, and operational issues; partner with scientific, operational, Facilities, EHS, and support teams to resolve issues and enable execution.
- Manage purchasing, inventory, supplies, shared resources, sample tracking, and freezer storage for material availability and organization; coordinate compliant domestic and international shipments of laboratory materials, biological samples, and research supplies.
- Coordinate equipment lifecycle, including installation, qualification, calibration, preventive maintenance and repairs.
- Partner with EHS on safety compliance, inspections, training, incident follow-up, and corrective actions; support employee onboarding, lab access, required training, and daily site coordination.
- Analyze lab performance, equipment reliability, utilization, and inventory trends to mitigate operational risks and recommend resource or investment priorities to leadership.
- Develop and execute a long-term lab operations strategy and roadmap aligned with TCT priorities, growth, and evolving capability needs.
- Resolve complex operational issues, make decisions with limited direction, and communicate recommendations to leadership.
- Demonstrated ability to influence and lead across scientific, engineering, facilities, safety, and vendor organizations without direct authority.