Purpose:
AbbVie’s CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through preclinical development. You will work at the intersection of synthetic biology and immune modulation. The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs.
Key Responsibilities:
- Design and execute in vitro assays to evaluate CAR-T biology, including assessment of cytotoxicity, T-cell effector function, and immune cell phenotyping.
- Independently establish, track, and deliver on project milestones and experimental timelines, ensuring alignment with program objectives and organizational priorities, while adapting to evolving scientific needs.
- Organize, analyze, and synthesize complex scientific data, and effectively communicate experimental strategies, results, and interpretations to internal and external stakeholders through clear and impactful presentations and scientific reports.
- Maintain comprehensive and well-documented records in an Electronic Lab Notebook (ELN).