Senior Scientist, I

Seeking a highly motivated candidate for the position of Senior Scientist I to join the Antibody Drug Conjugate (ADC) Process Development group located in North Chicago, IL.  This team is part of the Process Development Science and Technology (PDS&T) group at AbbVie.  In this role, the candidate will support process development of Antibody Drug Conjugates (ADCs) and other conjugation modalities.  The candidate will design and perform experiments related to ADC conjugation and purification unit operations, analyze experimental results and analytical dates from those experiments.  This development work will support process characterization, technology transfer, and regulatory submissions for ADC programs in AbbVie’s pipeline.  The candidate must possess a strong technical background, effective communication skills and an ability to work cross functionally with Analytical, Engineering, Manufacturing teams.

Responsibilities:

• Routinely demonstrate scientific initiative and creativity in research or development activities.
• Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
• Formulate conclusions and design follow-on experiments based on multidisciplinary data.
• May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
• A primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
• Demonstrates high proficiency across a wide range of relevant technologies.
• Maintain a high level of productivity in the lab and/or pilot plant.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.
• Direct mentorship of others.
• Perform ADC conjugation and purification operations at reaction scales ranging from lab to pilot-scale.
• Perform routine sample preparation and operation of HPLC-based analytical assays.