The Quantitative, Translational & ADME Sciences (QTAS) Department at AbbVie, Inc. in North Chicago, IL is seeking a Scientist I to join the Non-Regulated Bioanalysis group. This role supports high-throughput processing of samples from biological matrices and LC-MS/MS-based bioanalysis. The ideal candidate will have experience in bioanalytical sample preparation using a range of extraction techniques, operational workflows, data analysis, review, and reporting.
This position is well suited for a detail-oriented, motivated scientist who thrives in a fast-paced, collaborative environment and is committed to delivering high-quality results across multiple projects under tight deadlines. The role also involves partnering with cross-functional teams to align bioanalytical processes with scientific and business needs.
Key Responsibilities
Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies
Conduct and optimize sample extraction using protein precipitation, liquid/liquid extraction, or solid-phase extraction methods
Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs, Sciex 5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst, Sciex OS, and MassHunter
Troubleshoot pre-analytical and bioanalytical issues
Maintain accurate documentation of work, including LIMS records, electronic notebooks, test methods, and protocols
Collaborate with teams across Discovery and QTAS to support bioanalysis
Train and mentor junior scientists as needed
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