AbbVie Process Chemistry is responsible for the chemical development of AbbVie’s clinical candidates. We are looking for a highly motivated Principal Research Scientist II who can make scientific contributions and develop strategies, timelines and key activities across drug substance modalities, including small molecules. The candidate must be able to mentor and develop staff with experimental approaches to solve difficult scientific and technical challenges. The candidate will be an integral part of project teams and will be responsible for developing the synthetic process and executing activities required for drug substance process development. Working with cross-functional colleagues, the candidate will develop productive collaborations and communications with scientific teams.
Responsibilities:
- The candidate will participate and/or lead project teams associated with drug substance process development and characterization.
- Develop and characterize drug substance processes in the laboratory and translate them to scalable processes.
- Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management. Mentor staff in troubleshooting strategic and experimental issues.
- Author and review key regulatory documents, laboratory data, technical memos and reports.
- The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug product development, and program management.
- The candidate will identify and nurture ideas for continuous improvement activities and initiatives within the department.
- The candidate will be responsible for setting project strategies, defining project responsibilities and timelines, developing control strategies, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing.