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Job Title

Postdoctoral Fellow - Jianjun Wu Lab

Location

Cleveland

Facility

Cleveland Clinic Main Campus

Department

Job Code

X1004

Shift

Variable

Schedule

12:00am-12:00am

Job Summary

Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through Cleveland Clinic Research. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Job Details

NIH NRSA Postdoctoral Salary Scale

Years of Experience: Stipend for FY 2026

0: $63,480
1: $63,900
2: $64,380
3: $66,948
4: $69,180
5: $71,748
6: $74,424
7 or More: $77,076

We are currently seeking highly motivated Postdoc Fellows to join our research team in the Center for Immunotherapy & Precision Immuno-Oncology at Cleveland Clinic Lerner Research Institute. The Wu lab is interested in understanding the fundamental mechanism of innate immunity and its impact on adaptive immunity, inflammation, and cancer. Dr. Wu’s lab is currently employing multifaceted approaches and mouse disease models to uncover the novel immunostimulatory or immunosuppressive mechanisms of cGAS-STING pathway in antitumor immunity and autoimmunity. The overarching goal of the Wu lab is to harness innate immunity to develop new immunotherapies for cancer and inflammatory diseases.

Our recent research has been published in top-tier journals, including Immunity (PMIDs: 40010341, 32640258), PNAS (PMID: 38985760), Journal of Experimental Medicine (PMID: 30886058), and Cell Host & Microbe (PMID: 26320998). Our research is currently supported by multiple prestigious awards, including the NIH MERIT Award, Mathers Foundation Award, V Scholar Award, MRA Young Investigator Award, and ACS Catalyst Award, among others. The ideal candidates should have a PhD degree and have a strong background and/or interest in molecular biology, innate immunity, or cancer immunology. Proficient laboratory skills and highly self-motivation are required. Applicants with experience in immunology are preferred.

Principal Investigator: Jianjun Wu, PhD

Cleveland Clinic Research Department: Cancer Sciences

Lab Research Topics:

Innate Immunity
T cell biology
Cancer Immunology
Molecular biology
STING signaling

For more information about the lab's research, please visit: https://www.lerner.ccf.org/immunotherapy/wu/ or contact Dr. Wu at wuj9@ccf.org

Responsibilities:

Project design with the goal of data generation, analysis, interpretation
Conducts research focused on Innate Immunity & Cancer Immunology
Prepare manuscripts for publication, presentation and future research
Plans, organizes, performs and monitors daily project protocols

Education:

PhD or MD/PhD required
MD with relevant laboratory experience may substitute for PhD

Languages:

English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

Previous experience in a research or academic setting. Graduate student experience meets this requirement.
Scientific writing experience

Additional Preferred Qualities:

PhD in an appropriate scientific field such as Molecular biology, Immunology, Microbiology, Cell biology, Biochemistry, or other similar science major.
Requires critical thinking skills and decisive judgment

Physical Requirements:

Ability to perform work in a stationary position for extended periods
Ability to operate a computer and other office equipment
Ability to communicate and exchange accurate information
Ability to distinguish color
Manual dexterity to handle specimens and repair equipment
Ability to lift and transport equipment or specimens weighing up to 20 pounds
May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

All application materials should be submitted directly via email to Jianjun Wu at wuj9@ccf.org

Curriculum vitae
A summary of current and future research interests
Expected availability date
Three references

Keywords: Postdoc, Research, LRI, Innate immunity, T cell biology, Cancer immunology, Molecular biology, STING biology, Immunotherapy

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.

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