Position Summary:
The Scientist in LGC Axolabs Process Development will be responsible for independent optimization of scale up/down solid-phase oligonucleotide synthesis, purification, concentration, conjugation, and downstream processing steps in preparation for handover to routine manufacturing. This role involves working with cross-functional teams to ensure successful execution of each campaign including troubleshooting technical issues.
LGC Axolabs has an extensive, ever-evolving global client base along with impressive technical capabilities within a state-of-the-art GMP facility. As the needs for the organization continue to grow, we are seeking technically skilled and motivated candidates who can contribute to innovative solutions in oligonucleotide process development. The successful candidate will be detail-oriented, proficient in chemistry techniques, and capable of working independently while collaborating across teams to meet project goals. The Scientist will work under the guidance of a Lead Senior Scientist and/or the Process Development Manager and will interface with internal and external stakeholders.
Areas of Responsibility:
The Scientist is responsible for independent optimization and execution of all unit operations of custom oligonucleotide manufacturing including but not limited to: solid phase synthesis, cleavage and deprotection, preparative HPLC purification, conjugation chemistry, ultrafiltration/diafiltration, and lyophilization. Also included will be sample preparation of samples to the Analytical Development Team.
To perform this job successfully, an individual must be able to perform each essential function satisfactorily.
Essential Functions:
Shift hours: Monday through Thursday, 8:00 a.m. to 6:00 p.m. PT