People Operations Manager

BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making.

The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment.

This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.

Responsibilities:

• Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
• Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
• Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
• Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
• Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
• Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
• Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed

Qualifications:

• 5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
• Strong expertise in benefits administration and vendor management
• Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
• Demonstrated ability to design and improve scalable processes and systems
• Strong analytical skills with experience using data to drive decisions
• Excellent project management, organizational, and prioritization skills
• Strong communication skills with the ability to influence and partner across levels
• High attention to detail, sound judgment, and a proactive mindset
• “Scrappy,” solutions-oriented approach with a focus on continuous improvement
• Previous experience in start-up is highly desired

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.