Design and execute experiments for production of proteins using microbial fermentation processes. Design, analyze and interpret lab experiments, purification data, in-process trends, productivity and quality attributes to support upstream process development.
Lead efforts to evaluate different fermentation media, feeds, and feeding strategies to improve product yield and quality including proper folding of protein
Scale up process developed at research stage to manufacture adequate amounts of protein to support clinical trials
Author technical documentation including process validation protocols and reports. Evaluate process robustness, investigate causes of process variances, and take steps to maximize process reproducibility.
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