Upstream Process Development Scientist
Experience in development of mammalian cell culture processes for the production of recombinant proteins is a plus. ⢠Knowledge of protein chemistry and purification techniques and purification process development experience is preferred. ⢠Basic knowledge of cGMP policies and procedures. Basic knowledge of regulatory requirements of the pharmaceutical / biotechnology industry.
Key Responsibilities:
⢠Design and execute experiments for production of proteins using microbial fermentation processes.     Design, analyze and interpret lab experiments, purification data, in-process trends, productivity and quality attributes to support upstream process development.
⢠Lead efforts to evaluate different fermentation media, feeds, and feeding strategies to improve product yield and quality including proper folding of protein
⢠Scale up process developed at research stage to manufacture adequate amounts of protein to support clinical trials
⢠Author technical documentation including process validation protocols and reports.
Evaluate process robustness, investigate causes of process variances, and take steps to maximize process reproducibility.
Integrated Resources INC
https://careers.smartrecruiters.com/IntegratedResourcesINC