Upstream Process Development Scientist

Key Responsibilities:

• Design and execute experiments for production of proteins using microbial fermentation processes.

Design, analyze and interpret lab experiments, purification data, in-process trends, productivity and

quality attributes to support upstream process development.

• Lead efforts to evaluate different fermentation media, feeds, and feeding strategies to improve

product yield and quality including proper folding of protein

• Scale up process developed at research stage to manufacture adequate amounts of protein to support

clinical trials

• Author technical documentation including process validation protocols and reports. Evaluate process

robustness, investigate causes of process variances, and take steps to maximize process reproducibility.