Development Specialist

Job Title: Development Specialist 

Location: Lexington, MA

Duration: 6 Months+ (Possible Ext.)

Job Summary:

This individual will contribute to purification process development. They will be responsible for performing laboratory and pilot scale column chromatography, Tangential flow filtration and analytical assays to support protein purification process development. The individual applies basic knowledge form various technical areas, industry practices and standards. Provides quality and productive output that is consistently timely, reliable and reproducible. The candidate must be customer focused, results oriented, science driven and embrace values. 

Responsibilities: 

• Perform batch mode and column chromatography in support of purification process development –35 % 

• Perform ultrafiltration and diafiltration in support of purification process development – 35%

• Analyze, summarize and document data – 20% 

• Interact with analytical development and cell culture groups as well as development and engineering groups to ensure proper information exchange – 10% 

• Report any unexpected observations and suggest possible explanations and resolutions. 

• Present data in group forums; suggest conclusions and experimental plans based on purification fundamentals. 

• Examine literature and provide summaries in support of interpretations for experimental outcomes. 

• Report to supervisor in the purification group within BioProcess Development group. .

Education & Experience Requirements: 

• MS BS (0-2 years) (in Chemical/Biochemical Engineering or related discipline with relevant industry experience. 

• Product and purification process development experience in the biotechnology/pharmaceutical industry with practical experience around scale-up, technology transfer and manufacturing support of large scale GMP operations is desired.

• Familiarity with the operation of large scale purification equipment for chromatographic and filtration unit operations is desired. 

• Engineering degree preferred. 

• Keeps current with literature and latest technology developments, particularly in the area of separations.