• The Global Bio-therapeutic Technologies department has a contractor position in the Biophysics, Bio-analytics and Bio-conjugation group supporting the End-to-End Biologics initiative to develop an in silico computational tool that can predict the viscosity of antibodies and enable molecular engineering for improved develop-ability
• The scientist will provide experimental viscosity data for a library of antibodies as well as various biophysical characterizations such as DSC and aSEC to ensure these engineered variants retain the desired stability attributes
• Molecular assessment of the engineered variants using various bioanalytical techniques (i.e., DSC, DLS, aSEC)
• Generate viscosity data using Anton-Parr rheometer
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