Associate Scientist II

Job Title: Associate Scientist II

Location: Cambridge, MA
Duration: 12+ months (Possibility of extension)

Job Roles & Responsibilities

·This position is within the Alzheimer Research group.

·The successful candidate will be involved with the design and execution of experiments to support the discovery of Client drug targets and the development of small and large molecule drugs for the treatment of neurodegenerative diseases.

·He/she would be expected to work in a fast paced and highly collaborative team environment, and perform independent basic science and drug discovery research using the highest scientific standards.

·He/she will be responsible for designing, executing and analysing in vitro and in vivo experiments, as part of a larger research project.

Qualifications

·Possess excellent understanding of basic neurobiology of neurodegenerative diseases and mechanisms of neurodegeneration.

·Demonstrate keen knowledge of experimental design, underlying scientific principles, and the ability to analyse and assess results.

·Possess significant expertise in animal models of neurodegenerative diseases, especially Alzheimer-related models, and experience with handling and dosing of rodents, tissues and fluids collection (CSF, plasma).

·Possess significant experience in immunohistopathological techniques, including tissue processing and sectioning, immunostaining, microscopy techniques and image analysis.

·Possess significant experience in a variety of biochemical analytical methods, including gel electrophoresis, Western blot, ELISA, protein extraction.

·Possess significant experience in a variety of cell biology methods, including cell lines and primary neurons cultures, transfection, cell imaging (ICC, IF)

·Qualified candidates must demonstrate strong interpersonal and organizational skills, and the ability to maintain detailed written records of research.

Education

·MS in biological sciences and minimal 5 years of relevant experience in academia or industry.

·Candidates with PhD's will not be a fit for this role