Job Description:
Job Title: Clinical-Scientific - Bench Scientist I
Location: Chesterfield – MO
Duration: 12 Months+
- The Associate Scientist position is available within the Conjugation and Polytides Process Development (CPPD) group in Bioprocess R&D. Working within a team setting, the successful applicant will support the development of innovative, robust, efficient, and scalable chemical and biochemical processes and technologies required for the advancement of a diverse and extensive portfolio of bio-conjugate- and polytide-derived bio therapeutics.
- The position will focus on providing analytical support for process characterization studies, but may also support fellow scientist in design and execution of experiments and the necessary purification activities to produce drug substances with appropriate quality attributes.
- The candidate will work across process development functions and projects covering a broad portfolio including vaccines, antibody-drug conjugates, therapeutic proteins, and oligonucleotides.
- Under the guidance of senior scientists, the candidate will perform basic analysis of process intermediates and drug substances.
- The candidate will also work with fellow scientists in designing and executing experiments at the laboratory scale, and based on the analyses of these studies, will be expected to develop and test new hypotheses to improve fundamental understanding of the chemical and biochemical processes, including bio-conjugation or large and small molecule combinations.
- This position will support drug substance and drug substance intermediate purification activities as needed.
- This position requires a highly motivated individual with the ability to work closely with other members of the laboratory and the department in a matrix environment.
- This position will also collaborate with the pilot plan and manufacturing staff on experimental studies, clinical manufacturing, and process validation, including work with external contract manufacturing organizations.
- Demonstrated ability to drive for results and drive innovative research programs independently.
- Good understanding of chemistry/biochemistry and macromolecule analytics.
- Familiarity with recent scientific literature is desirable.
- Applicants should be self-motivated, organized, and capable of working independently, and in a collaborative environment.
- The successful candidate will possess strong oral and written communication skills. Strong analytical and computer skills are required.